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CD4 immunoadhesin, but not recombinant soluble CD4, blocks syncytium formation by human immunodeficiency virus type 2-infected lymphoid cells.

Recombinant soluble CD4 (rCD4) has been shown to be an effective inhibitor of human immunodeficiency virus type 1 (HIV-1) and HIV-2 infection of lymphoid cells in vitro. In this report, we characterized the effects of rCD4, the V1V2 fragment of CD4, and the immunoadhesin CD4-immunoglobulin G on sync...

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Bibliographic Details
Published in:J Virol
Main Authors: Sekigawa, I, Chamow, S M, Groopman, J E, Byrn, R A
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1990
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248017/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2398542/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.10.5194-5198.1990
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