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DNA Overstretching in the Presence of Glyoxal: Structural Evidence of Force-Induced DNA Melting

When a long DNA molecule is stretched beyond its B-form contour length, a transition occurs in which its length increases by a factor of 1.7, with very little force increase. A quantitative model was proposed to describe this transition as force-induced melting, where double-stranded DNA is converte...

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Main Authors: Shokri, Leila, McCauley, Micah J., Rouzina, Ioulia, Williams, Mark C.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2479620/
https://ncbi.nlm.nih.gov/pubmed/18424499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.132688
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