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Production of novel polyphosphoinositides in vivo is linked to cell transformation by polyomavirus middle T antigen.

Phosphatidylinositol 3-kinase associates with the polyomavirus middle T antigen (PyMTAg)-pp60c-src complex in polyomavirus-transformed cells. Here we show that anti-PyMTAg immunoprecipitates from PyMTAg-transformed NIH 3T3 cells have lipid kinase activities that phosphorylate phosphatidylinositol, p...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Serunian, L A, Auger, K R, Roberts, T M, Cantley, L C
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1990
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247958/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2168961/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.10.4718-4725.1990
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