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Developmental changes in calcium/calmodulin-dependent inactivation of calcium currents at the rat calyx of Held

Ca(2+)-binding to calmodulin (CaM) causes facilitation and/or inactivation of recombinant Ca(2+) channels. At the rat calyx of Held, before hearing onset, presynaptic Ca(2+) currents (I(pCa)) undergo Ca(2+)/CaM-dependent inactivation during repetitive activation at around 1 Hz, implying that this ma...

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Detalhes bibliográficos
Main Authors: Nakamura, Takeshi, Yamashita, Takayuki, Saitoh, Naoto, Takahashi, Tomoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2479563/
https://ncbi.nlm.nih.gov/pubmed/18238813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.142521
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