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Peri-implantation and late gestation maternal undernutrition differentially affect fetal sheep skeletal muscle development

Poor prenatal nutrition is associated with a greater risk of adult glucose intolerance and insulin insensitivity in the offspring. Skeletal muscle is the primary tissue for glucose utilization, and insulin resistance in muscle is the earliest identifiable abnormality in the pre-diabetic patient. We...

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Bibliographic Details
Main Authors: Costello, Paula M, Rowlerson, Anthea, Astaman, Nur Aida, Anthony, Fred Erick W, Sayer, Avan Aihie, Cooper, Cyrus, Hanson, Mark A, Green, Lucy R
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2479554/
https://ncbi.nlm.nih.gov/pubmed/18339691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.150987
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