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Macrophage-tropic strains of human immunodeficiency virus type 1 utilize the CD4 receptor.

To characterize the role of CD4 in human immunodeficiency virus type 1 (HIV-1) infection of macrophages, we examined the expression of CD4 by primary human monocyte-derived macrophages and studied the effect of recombinant soluble CD4 and anti-CD4 monoclonal antibodies on HIV-1 infection of these ce...

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Udgivet i:J Virol
Principais autores: Collman, R, Godfrey, B, Cutilli, J, Rhodes, A, Hassan, N F, Sweet, R, Douglas, S D, Friedman, H, Nathanson, N, Gonzalez-Scarano, F
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247917/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2200889/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.9.4468-4476.1990
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