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Immunization of mice with recombinant vaccinia virus expressing authentic dengue virus nonstructural protein NS1 protects against lethal dengue virus encephalitis.

The protective immunity conferred by a set of recombinant vaccinia viruses containing the entire coding sequence of dengue virus type 4 nonstructural glycoprotein NS1 plus various flanking sequences was evaluated by using a mouse encephalitis model. Mice immunized with recombinant vNS1-NS2a, which e...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Falgout, B, Bray, M, Schlesinger, J J, Lai, C J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1990
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247903/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2143542/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.9.4356-4363.1990
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