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Temperature-sensitive mutants of Abelson murine leukemia virus deficient in protein tyrosine kinase activity.

The effect of two missense mutations in abl on transformation by Abelson murine leukemia virus was evaluated. These mutations led to the substitution of a histidine for Tyr-590 and a glycine for Lys-536. Both changes gave rise to strains that were temperature dependent for transformation of both NIH...

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Bibliografische gegevens
Hoofdauteurs: Engelman, A, Rosenberg, N
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1990
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC247889/
https://ncbi.nlm.nih.gov/pubmed/1696637
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