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Mitochondrial Targeting Adaptation of the Hominoid-Specific Glutamate Dehydrogenase Driven by Positive Darwinian Selection

Many new gene copies emerged by gene duplication in hominoids, but little is known with respect to their functional evolution. Glutamate dehydrogenase (GLUD) is an enzyme central to the glutamate and energy metabolism of the cell. In addition to the single, GLUD-encoding gene present in all mammals...

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Detalhes bibliográficos
Main Authors: Rosso, Lia, Marques, Ana C., Reichert, Andreas S., Kaessmann, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2478720/
https://ncbi.nlm.nih.gov/pubmed/18688271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000150
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