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No Major Change in vCJD Agent Strain after Secondary Transmission via Blood Transfusion

BACKGROUND: The identification of transmission of variant Creutzfeldt-Jakob disease (vCJD) by blood transfusion has prompted investigation to establish whether there has been any alteration in the vCJD agent following this route of secondary transmission. Any increase in virulence or host adaptation...

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Detalhes bibliográficos
Main Authors: Bishop, Matthew T., Ritchie, Diane L., Will, Robert G., Ironside, James W., Head, Mark W., Thomson, Val, Bruce, Moira, Manson, Jean C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2478718/
https://ncbi.nlm.nih.gov/pubmed/18682737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002878
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