C-Peptide Prevents Hippocampal Apoptosis in Type 1 Diabetes

To explore mechanisms underlying central nervous system (CNS) complications in diabetes, we examined hippocampal neuronal apoptosis and loss, and the effect of C-peptide replacement in type 1 diabetic BB/W rats. Apoptosis was demonstrated after 8 months of diabetes, by DNA fragmentation, increased n...

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Detalhes bibliográficos
Main Authors: Li, Zhen-guo, Zhang, Weixian, Sima, Anders A. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2478591/
https://ncbi.nlm.nih.gov/pubmed/12546277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15604280214936
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2478591/
https://ncbi.nlm.nih.gov/pubmed/12546277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15604280214936