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An Amsacta moorei entomopoxvirus ortholog of the poly(A) polymerase small subunit exhibits methyltransferase activity and is non-essential for virus growth

Unlike the heterodimeric poly(A) polymerase (PAP) of vaccinia virus (VACV), the PAP from the Amsacta moorei entomopoxvirus, AMEV, is potentially derived from three subunits: a single large and two small subunits (AMV060 and AMV115). The VACV small subunit serves as a 2′-O-methyltransferase, a proces...

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Autores principales: Becker, Marie N., Todd, Tracie M., Moyer, Richard W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2478561/
https://ncbi.nlm.nih.gov/pubmed/18367228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.02.023
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