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Glucose-dependent and Glucose-sensitizing Insulinotropic Effect of Nateglinide: Comparison to Sulfonylureas and Repaglinide

Nateglinide, a novel D-phenylalanine derivative, stimulates insulin release via closure of K(ATP) channels in pancreatic β-cell, a primary mechanism of action it shares with sulfonylureas (SUs) and repaglinide. This study investigated (1) the influence of ambient glucose levels on the insulinotropic...

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Detalhes bibliográficos
Main Authors: Hu, Shiling, Wang, Shuya, Dunning, Beth E.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2478524/
https://ncbi.nlm.nih.gov/pubmed/12369728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/EDR.2001.63
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