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Mutational analysis of the conserved basic domain of human immunodeficiency virus tat protein.

The tat trans-activators encoded by the known strains of primate immunodeficiency virus share a conserved, highly basic protein domain. Mutagenesis of this sequence in the tat gene of human immunodeficiency virus type 1 is shown here to reduce, but not eliminate, the trans-activation of human immuno...

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Autors principals: Hauber, J, Malim, M H, Cullen, B R
Format: Artigo
Idioma:Inglês
Publicat: 1989
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC247813/
https://ncbi.nlm.nih.gov/pubmed/2536828
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