A novel multigene family encodes diversified variable regions

Antigen recognition in the adaptive immune response by Ig and T-cell antigen receptors (TCRs) is effected through patterned differences in the peptide sequence in the V regions. V-region specificity forms through genetically programmed rearrangement of individual, diversified segmental elements in s...

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Autori principali: Strong, Scott J., Mueller, M. Gail, Litman, Ronda T., Hawke, Noel A., Haire, Robert N., Miracle, Ann L., Rast, Jonathan P., Amemiya, Chris T., Litman, Gary W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC24776/
https://ncbi.nlm.nih.gov/pubmed/10611341
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