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Linker insertion-deletion mutagenesis of the v-src gene: isolation of host- and temperature-dependent mutants.

The host cell regulators and substrates of the Rous sarcoma virus transforming protein pp60v-src remain largely unknown. Viral mutants which induce a host-dependent phenotype may result from mutations which affect the interaction of pp60v-src with host cell components. To isolate such mutants and to...

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Bibliographic Details
Published in:J Virol
Main Authors: DeClue, J E, Martin, G S
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1989
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247722/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2536090/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.2.542-554.1989
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