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The reduced virulence of the thymotropic Moloney murine leukemia virus derivative MoMuLV-TB is mapped to 11 mutations within the U3 region of the long terminal repeat.

Chimeric constructs were generated by exchanging genomic fragments between the potent T-cell lymphoma inducer Moloney murine leukemia virus (MoMuLV) and its derivative MoMuLV-TB, which induces T-cell lymphoma after a relatively longer latent period. Analysis of the T-cell lymphoma-inducing potential...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Yuen, P H, Szurek, P F
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1989
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247715/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2783465/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.2.471-480.1989
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