Leader-to-leader splicing is required for efficient production and accumulation of polyomavirus late mRNAs.

Polyomavirus late mRNA molecules contain multiple, tandem copies of a noncoding 57-base "late leader" exon at their 5' ends. This exon is encoded only once in the genome. Leader multiplicity arises from leader-leader splicing in giant primary transcripts, which are the result of multiple circuits of...

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Pubblicato in:	J Virol
Autori principali:	Adami, G R, Marlor, C W, Barrett, N L, Carmichael, G G
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247660/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2535755/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.1.85-93.1989
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