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Universality of J-Shaped and U-Shaped Dose-Response Relations as Emergent Properties of Stochastic Transition Systems
Dose-response data for many chemical carcinogens exhibit multiple apparent concentration thresholds. A relatively small increase in exposure concentration near such a threshold disproportionately increases incidence of a specific tumor type. Yet, many common mathematical models of carcinogenesis do...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Hormesis Society
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2475946/ https://ncbi.nlm.nih.gov/pubmed/18648616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2203/dose-response.0003.03.006 |
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