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Retinoic Acid Promotes the Generation of Pancreatic Endocrine Progenitor Cells and Their Further Differentiation into β-Cells

The identification of secreted factors that can selectively stimulate the generation of insulin producing β-cells from stem and/or progenitor cells represent a significant step in the development of stem cell-based β-cell replacement therapy. By elucidating the molecular mechanisms that regulate the...

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Detalhes bibliográficos
Main Authors: Öström, Maria, Loffler, Kelly A., Edfalk, Sara, Selander, Lars, Dahl, Ulf, Ricordi, Camillo, Jeon, Jongmin, Correa-Medina, Mayrin, Diez, Juan, Edlund, Helena
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475501/
https://ncbi.nlm.nih.gov/pubmed/18665267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002841
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