TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation

INTRODUCTION: Signaling downstream of Ras is mediated by three major pathways, Raf/ERK, phosphatidylinositol 3 kinase (PI3K), and Ral guanine nucleotide exchange factor (RalGEF). Ras signal transduction pathways play an important role in breast cancer progression, as evidenced by the frequent over-e...

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Bibliografske podrobnosti
Main Authors: Oberst, Michael D, Beberman, Stacey J, Zhao, Liu, Yin, Juan Juan, Ward, Yvona, Kelly, Kathleen
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474852/
https://ncbi.nlm.nih.gov/pubmed/18597688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-189
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