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TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation
INTRODUCTION: Signaling downstream of Ras is mediated by three major pathways, Raf/ERK, phosphatidylinositol 3 kinase (PI3K), and Ral guanine nucleotide exchange factor (RalGEF). Ras signal transduction pathways play an important role in breast cancer progression, as evidenced by the frequent over-e...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2474852/ https://ncbi.nlm.nih.gov/pubmed/18597688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-189 |
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