Insulin gene polymorphisms in type 1 diabetes, Addison's disease and the polyglandular autoimmune syndrome type II

BACKGROUND: Polymorphisms within the insulin gene can influence insulin expression in the pancreas and especially in the thymus, where self-antigens are processed, shaping the T cell repertoire into selftolerance, a process that protects from β-cell autoimmunity. METHODS: We investigated the role of...

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Détails bibliographiques
Auteurs principaux: Ramos-Lopez, Elizabeth, Lange, Britta, Kahles, Heinrich, Willenberg, Holger S, Meyer, Gesine, Penna-Martinez, Marissa, Reisch, Nicole, Hahner, Stefanie, Seissler, Jürgen, Badenhoop, Klaus
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2008
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474835/
https://ncbi.nlm.nih.gov/pubmed/18620562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-9-65
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