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Improved Protocol for Asymmetric, Intramolecular Heteroatom Michael Addition Using Organocatalysis: Enantioselective Syntheses of Homoproline, Pelletierine, and Homopipecolic Acid

An improved protocol for the construction of enantioenriched pyrrolidine, indoline, and piperidine rings using an organocatalyzed, intramolecular heteroatom Michael addition is described. Application to the enantioselective synthesis of homoproline, homopipecolic acid, and pelletierine has been acco...

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Detalhes bibliográficos
Main Authors: Carlson, Erik C., Rathbone, Lauren K., Yang, Hua, Collett, Nathan D., Carter, Rich G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474690/
https://ncbi.nlm.nih.gov/pubmed/18529081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo800749t
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