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ATP Release from Vascular Endothelia Occurs Across Cx43 Hemichannels and Is Attenuated during Hypoxia

BACKGROUND: Extracellular ATP is an important signaling molecule for vascular adaptation to limited oxygen availability (hypoxia). Here, we pursued the contribution of vascular endothelia to extracellular ATP release under hypoxic conditions. METHODOLOGY, PRINCIPAL FINDINGS: We gained first insight...

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Detalhes bibliográficos
Main Authors: Faigle, Marion, Seessle, Jessica, Zug, Stephanie, El Kasmi, Karim C., Eltzschig, Holger K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474679/
https://ncbi.nlm.nih.gov/pubmed/18665255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002801
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