EVI1 activation in blast crisis CML due to juxtaposition to the rare 17q22 partner region as part of a 4-way variant translocation t(9;22)

BACKGROUND: Variant translocations t(9;22) occur in 5 to 10% of newly diagnosed CMLs and additional genetic changes are present in 60–80% of patients in blast crisis (BC). Here, we report on a CML patient in blast crisis presenting with a four-way variant t(9;22) rearrangement involving the EVI1 loc...

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Bibliografische gegevens
Hoofdauteurs: De Weer, An, Poppe, Bruce, Cauwelier, Barbara, Carlier, Andre, Dierick, Jan, Verhasselt, Bruno, Philippé, Jan, Van Roy, Nadine, Speleman, Frank
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2008
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474635/
https://ncbi.nlm.nih.gov/pubmed/18613965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-193
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