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Retinoic acid induces caspase-8 transcription via phospho-CREB and increases apoptotic responses to death stimuli in neuroblastoma cells

Caspase-8 is frequently deleted or silenced in neuroblastoma and other solid tumor such as medulloblastoma and small cell lung carcinoma. Caspase-8 expression can be re-established in neuroblastoma cell lines by treatment with demethylating agents or with IFN-γ Here we show that four different retin...

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Bibliografski detalji
Glavni autori: Jiang, Manrong, Zhu, Kejin, Grenet, Jose, Lahti, Jill M.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474548/
https://ncbi.nlm.nih.gov/pubmed/18342014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2008.02.007
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