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Long-term suppression of Leydig cell steroidogenesis prevents Leydig cell aging

Male aging is accompanied by reduced testosterone production by the Leydig cells, the testosterone-producing cells of the testis. The mechanism by which this occurs is unknown. Based on the observations that reactive oxygen is capable of damaging components of the steroidogenic pathway and that reac...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Chen, Haolin, Zirkin, Barry R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1999
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24741/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10611306/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.26.14877
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