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Induction of Cycloheximide-Resistant Mutants in Saccharomyces cerevisiae with N-Methyl-N′-Nitro-N-Nitrosoguanidine and ICR-170

N-Methyl-N′-nitro-N-nitrosoguanidine (MNNG) induces cycloheximide-resistant mutations in Saccharomyces cerevisiae, but few, if any, resistant mutants are induced by the acridine mustard ICR-170. Cycloheximide sensitivity in yeast is associated with the ribosome, and treatment with the antibiotic at...

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Bibliographic Details
Published in:J Bacteriol
Main Author: Brusick, David J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1972
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247334/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4551745/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.109.3.1134-1138.1972
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