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Conditional Lethality of recA and recB Derivatives of a Strain of Escherichia coli K-12 with a Temperature-Sensitive Deoxyribonucleic Acid Polymerase I

We have isolated a strain of Escherichia coli K-12 carrying a mutation, polA12, that results in the synthesis of a temperature-sensitive deoxyribonucleic acid (DNA) polymerase I. The double mutants polA12 recA56 and polA12 recB21, constructed at 30 C, are inviable at 42 C. About 90% of the cells of...

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Bibliographic Details
Published in:J Bacteriol
Main Authors: Monk, M., Kinross, J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1972
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247316/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4551758/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.109.3.971-978.1972
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