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A family of membrane-embedded metalloproteases involved in regulated proteolysis of membrane-associated transcription factors

We present evidence that the sporulation protein SpoIVFB of Bacillus subtilis is a member of a newly recognized family of metalloproteases that have catalytic centers adjacent to or within the membrane. SpoIVFB is required for converting the membrane-associated precursor protein, pro-σ(K), to the ma...

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Autori principali: Rudner, David Z., Fawcett, Paul, Losick, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC24722/
https://ncbi.nlm.nih.gov/pubmed/10611287
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