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Mechanism of Action of Rifampin on Mycobacterium smegmatis

Deoxyribonucleic acid (DNA)-dependent ribonucleic acid (RNA) polymerase (EC 2.7.7.6) isolated from a rifampin-sensitive strain of Mycobacterium smegmatis was 90% inhibited by 1 μg of rifampin per ml; enzyme from a rifampin-resistant mutant was not affected by this concentration of antibiotic. Inhibi...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Principais autores: White, R. J., Lancini, G. C., Silvestri, L. G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1971
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247133/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4942761/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.108.2.737-741.1971
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