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A cyclodextrin dimer with a photocleavable linker as a possible carrier for the photosensitizer in photodynamic tumor therapy

A cyclodextrin dimer has been synthesized with two β-cyclodextrins linked by a flexible chain containing a carbon–carbon double bond. This dimer binds and solubilizes a phthalocyanine-based photosensitizer that generates singlet oxygen on irradiation. When the complex is irradiated, the singlet oxyg...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Ruebner, Anja, Yang, Zhiwei, Leung, David, Breslow, Ronald
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24709/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10611274/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.26.14692
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