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Slow skeletal troponin I gene transfer, expression, and myofilament incorporation enhances adult cardiac myocyte contractile function

The functional significance of the developmental transition from slow skeletal troponin I (ssTnI) to cardiac TnI (cTnI) isoform expression in cardiac myocytes remains unclear. We show here the effects of adenovirus-mediated ssTnI gene transfer on myofilament structure and function in adult cardiac m...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Westfall, Margaret V., Rust, Elizabeth M., Metzger, Joseph M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24698/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9144257/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.10.5444
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