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Enriched Selection of Dominant Mutations: Histidine Operator Mutations

In the course of selection of bacteria with derepressed levels of histidine biosynthetic enzymes, it was found that when mutagen-treated cells were spread on a selective medium without allowing intervening growth to occur, the frequency of operator mutants obtained was dramatically increased. This m...

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Autori principali: Chang, George W., Straus, Daniel, Ames, Bruce N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1971
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC246966/
https://ncbi.nlm.nih.gov/pubmed/4939768
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