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The inhibition of antigen-presenting activity of dendritic cells resulting from UV irradiation of murine skin is restored by in vitro photorepair of cyclobutane pyrimidine dimers

Exposing skin to UVB (280–320 nm) radiation suppresses contact hypersensitivity by a mechanism that involves an alteration in the activity of cutaneous antigen-presenting cells (APC). UV-induced DNA damage appears to be an important molecular trigger for this effect. The specific target cells in the...

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Autors principals: Vink, Arie A., Moodycliffe, Angus M., Shreedhar, Vijay, Ullrich, Stephen E., Roza, Len, Yarosh, Daniel B., Kripke, Margaret L.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC24665/
https://ncbi.nlm.nih.gov/pubmed/9144224
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