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The effect of RGD peptides on osseointegration of hydroxyapatite biomaterials

Given that hydroxyapatite (HA) biomaterials are highly efficient at adsorbing proadhesive proteins, we questioned whether functionalizing HA with RGD peptides would have any benefit. In this study, we implanted uncoated or RGD-coated HA disks into rat tibiae for 30 minutes to allow endogenous protei...

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Detalhes bibliográficos
Main Authors: Hennessy, KM, Clem, WC, Phipps, MC, Sawyer, AA, Shaikh, FM, Bellis, SL
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2465812/
https://ncbi.nlm.nih.gov/pubmed/18440064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2008.04.014
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