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Identification of GATC- and CCGG- recognizing Type II REases and their putative specificity-determining positions using Scan2S—a novel motif scan algorithm with optional secondary structure constraints

Restriction endonucleases (REases) are DNA-cleaving enzymes that have become indispensable tools in molecular biology. Type II REases are highly divergent in sequence despite their common structural core, function and, in some cases, common specificities towards DNA sequences. This makes it difficul...

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Autors principals: Niv, Masha Y., Skrabanek, Lucy, Roberts, Richard J., Scheraga, Harold A., Weinstein, Harel
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2465807/
https://ncbi.nlm.nih.gov/pubmed/17972284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.21777
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