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Endothelial nitric oxide attenuates Na(+)/Ca(2+) exchanger-mediated vasoconstriction in rat aorta

BACKGROUND AND PURPOSE: The Na(+)/Ca(2+) exchanger (NCX) may be an important modulator of Ca(2+) entry and exit. The present study investigated whether NCX was affected by prostacyclin and nitric oxide (NO) released from the vascular endothelium, as NCX contains phosphorylation sites for PKA and PKG...

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Detalhes bibliográficos
Main Authors: Zhao, J, Majewski, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2465575/
https://ncbi.nlm.nih.gov/pubmed/18469841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.178
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