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Aberrant DNA methylation and gene expression in livers of newborn mice transplacentally exposed to a hepatocarcinogenic dose of inorganic arsenic

Our prior work showed that brief exposure of pregnant C3H mice to inorganic arsenic-induced hepatocellular carcinoma (HCC) formation in adult male offspring. The current study examined the early hepatic events associated with this oncogenic transformation. Pregnant mice were exposed to a known carci...

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Detalles Bibliográficos
Main Authors: Xie, Yaxiong, Liu, Jie, Benbrahim-Tallaa, Lamia, Ward, Jerry M., Logsdon, Daniel, Diwan, Bhalchandra A., Waalkes, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2465467/
https://ncbi.nlm.nih.gov/pubmed/17451858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2007.03.021
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