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Transgenerational effects of prenatal nutrient restriction on cardiovascular and hypothalamic-pituitary-adrenal function

The perinatal environment is a powerful determinant of risk for developing disease in later life. Here, we have shown that maternal undernutrition causes dramatic changes in heart structure and hypothalamo-pituitary-adrenal (HPA) function across two generations. Pregnant guinea pigs were fed 70% of...

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Detalhes bibliográficos
Main Authors: Bertram, Caroline, Khan, Omar, Ohri, Sunil, Phillips, David I, Matthews, Stephen G, Hanson, Mark A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2465204/
https://ncbi.nlm.nih.gov/pubmed/18292131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.147967
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