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Identification of longevity-associated genes in long-lived Snell and Ames dwarf mice

Recent landmark molecular genetic studies have identified an evolutionarily conserved insulin/IGF-1 signal transduction pathway that regulates lifespan. In C. elegans, Drosophila, and rodents, attenuated insulin/IGF-1 signaling appears to regulate lifespan and enhance resistance to environmental str...

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Detalhes bibliográficos
Main Authors: Boylston, W. H., DeFord, James H., Papaconstantinou, John
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2464723/
https://ncbi.nlm.nih.gov/pubmed/19943135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-006-9008-6
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