Noisy: Identification of problematic columns in multiple sequence alignments

MOTIVATION: Sequence-based methods for phylogenetic reconstruction from (nucleic acid) sequence data are notoriously plagued by two effects: homoplasies and alignment errors. Large evolutionary distances imply a large number of homoplastic sites. As most protein-coding genes show dramatic variations...

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Autors principals: Dress, Andreas WM, Flamm, Christoph, Fritzsch, Guido, Grünewald, Stefan, Kruspe, Matthias, Prohaska, Sonja J, Stadler, Peter F
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
Matèries:
Software Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2464588/
https://ncbi.nlm.nih.gov/pubmed/18577231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7188-3-7
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