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What does the T-cell receptor recognize when it docks on an MHC-encoded restricting element?
The postulate is analyzed that single V-gene segments encode recognition of the allele-specific determinants (a) required for the restrictive response of the αβTCR to peptide. The consequence of this is that the positively selected V-domain, Vα or Vβ, engages an allele-specific determinant (a) on on...
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2464364/ https://ncbi.nlm.nih.gov/pubmed/18394705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2008.02.016 |
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