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Charges dispersed over the permeation pathway determine the charge selectivity and conductance of a Cx32 chimeric hemichannel

Previous studies have shown that charge substitutions in the amino terminus of a chimeric connexin, Cx32*43E1, which forms unapposed hemichannels in Xenopus oocytes, can result in a threefold difference in unitary conductance and alter the direction and amount of open channel current rectification....

詳細記述

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書誌詳細
主要な著者: Oh, Seunghoon, Verselis, Vytas K, Bargiello, Thaddeus A
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Science Inc 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2464352/
https://ncbi.nlm.nih.gov/pubmed/18372303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.150805
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