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Mapmodulin: A possible modulator of the interaction of microtubule-associated proteins with microtubules

We have purified and characterized a 31-kDa protein named mapmodulin that binds to the microtubule-associated proteins (MAPs) MAP2, MAP4, and tau. Mapmodulin binds free MAPs in strong preference to microtubule-associated MAPs, and appears to do so via the MAP’s tubulin-binding domain. Mapmodulin inh...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Ulitzur, Nirit, Humbert, Martine, Pfeffer, Suzanne R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24635/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9144194/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.10.5084
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