Molecular uncoupling of C-C chemokine receptor 5-induced chemotaxis and signal transduction from HIV-1 coreceptor activity

The C-C chemokine receptor 5 (CCR5) plays a crucial role in facilitating the entry of macrophage-tropic strains of the HIV-1 into cells, but the mechanism of this phenomenon is completely unknown. To explore the role of CCR5-derived signal transduction in viral entry, we introduced mutations into tw...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Gosling, Jennifa, Monteclaro, Felipe S., Atchison, Robert E., Arai, Hidenori, Tsou, Chia-Lin, Goldsmith, Mark A., Charo, Israel F.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences of the USA 1997
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC24631/
https://ncbi.nlm.nih.gov/pubmed/9144190
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky