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Neutralizing VEGF Decreases Tortuosity and Alters Endothelial Cell Division Orientation in Arterioles and Veins in a Rat Model of ROP: Relevance to Plus Disease

PURPOSE: To study the effects of vascular endothelial growth factor (VEGF) on endothelial nitric oxide synthetase (eNOS) and retinal vascular tortuosity and cleavage planes in a rat model of retinopathy of prematurity (ROP). METHODS: Within 4 hours of birth, pups and mothers were cycled between 50%...

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Detalhes bibliográficos
Main Authors: Hartnett, M. Elizabeth, Martiniuk, David, Byfield, Grace, Geisen, Pete, Zeng, Gefei, Bautch, Victoria L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2459334/
https://ncbi.nlm.nih.gov/pubmed/18378573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-1780
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