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How much of protein sequence space has been explored by life on Earth?

We suggest that the vastness of protein sequence space is actually completely explorable during the populating of the Earth by life by considering upper and lower limits for the number of organisms, genome size, mutation rate and the number of functionally distinct classes of amino acids. We conclud...

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Bibliografiske detaljer
Main Authors: Dryden, David T.F, Thomson, Andrew R, White, John H
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2459213/
https://ncbi.nlm.nih.gov/pubmed/18426772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2008.0085
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