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Evolution of a New Gene Substituting for the leuD Gene of Salmonella typhimurium: Characterization of supQ Mutations
Alpha-isopropylmalate isomerase, the second specific enzyme in the biosynthesis of leucine, is coded for by two genes, leuC and leuD. Leucine auxotrophs, harboring leuD mutations including a deletion of the entire leuD gene, revert to leucine prototrophy owing to mutations at a locus, supQ, substant...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1974
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC245702/ https://ncbi.nlm.nih.gov/pubmed/4604457 |
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