Production of β-defensins by human airway epithelia

Human β-defensins (HBDs) are antimicrobial peptides that may play a role in mucosal defense. Diminished activity of these peptides has been implicated in the pathogenesis of cystic fibrosis (CF) lung disease. We show that HBD-1 and HBD-2 mRNAs are expressed in excised surface and submucosal gland ep...

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Detalhes bibliográficos
Main Authors: Singh, Pradeep K., Jia, Hong Peng, Wiles, Kerry, Hesselberth, Jay, Liu, Lide, Conway, Barbara-Ann D., Greenberg, Everett P., Valore, Erika V., Welsh, Michael J., Ganz, Tomas, Tack, Brian F., McCray, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24558/
https://ncbi.nlm.nih.gov/pubmed/9843998
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